STUDY OF OPPORTUNITY OF APPLICATION OF PHOTODYNAMIC THERAPY (PDT) WITH A PHOTOSENS.
Torshina N.L.1, Volkova A.I.1, Possyhanova A.M.1, Kogan E.A.2, Kharnas S.S.2.
1General Physics Institute
38 Vavilov st., Moscow 117942, Russia
2Medical Academy, clinic of surgeonly decease ?1
6 B. Pirogovskaya st., Moscow 119435, Russia
Currently we carry out the clinical examenation of Photosens preparation for treatment of cancer. It consists of aluminium sulpho-phtalocianine. At the moment we investigate new fotosensitisers and new application of Photosens.
We showed that Photosens is strongly accumulated not only in tumor but in inflamation and damage tissues.
For example we havent observed any anyaccumulation of Photosens on membrane of erithricites, but after membrane damage the accumulation was larger. In the nother case we showed that accumulation of Photosens in lung tissue was very small and also it became bigger in inflamation tissues.
At the another case when we investigated accumulation of Photosens in tumor we found out that accumulation rate was larger after damage of tumor tissues (fig. dr.). We even worked out our out method of treatment of cancer based on this phenomenon. Therefor it is not suprising that accumulation of Photosens have therapevtic value on sites of localisationof fungus bekause on this site we observed damage tissues anda lot of leikocites and macrofages.
In the experiment presented our aim was to treat the tumor of the dog mammary gland, we had the tumor with the fungus of types of Candida.
Therefore our investigation included two aims treatment of tumor and treatment of dermatomycosis.